An Electron Microscope Study of Mouse Mast Cells Arising in Vivo and in Vitro

نویسنده

  • John W. Combs
چکیده

Selective differentiation of cells morphologically identical with tissue mast cells at the light microscope level has been described by Ginsburg and Sachs (5) and Ginsburg and Lagunoff (4) in a mouse tissue culture system composed of a C3H feeder layer overplated with horse serum-sensitized C57BI lymphoid cells . Histochemical evaluation indicates that the granules of the tissue culturederived mast cells, like the granules of mast cells from normal mouse connective tissue, contain strongly acidic mucopolysaccharides and a chymotrypsin-like enzyme (4), further suggesting a homology between the tissue culture-derived mast cells and native mast cells . In this report, the degree of homology between mast cells arising in

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عنوان ژورنال:
  • The Journal of Cell Biology

دوره 48  شماره 

صفحات  -

تاریخ انتشار 1971